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During treatment with lexapro, sexual side effects -- such as ejaculation problems, impotence, or orgasm problems -- may develop. selective serotonin reuptake inhibitors like lexapro are known to cause certain sexual problems.. Is lexapro helpful for delayed ejaculation? can lexapro cause delayed ejaculation? lexapro is mentioned in 212 posts about delayed ejaculation. - page 2. Hi everybody i have been on lexapro for nearly 2 years. i was on the verge of getting inflammatory bowel disease from all the problems in my life..